Fatemeh Aghaziarati
, Mohammad-Taghi Chitsazi
* , Leila Roshangar
* , Amirreza Babaloo, Elnaz Ziaei-Rad
Abstract
Background: Maxillary sinus floor augmentation (MSFA) is commonly required in posterior maxillary atrophy. This study compared allogenic demineralized dentin matrix (ADDM) with a xenograft in MSFA. Methods: In this randomized split-mouth trial, 9 patients underwent bilateral MSFA with ADDM on one side and a xenograft on the other. Cone-beam computed tomography (CBCT) was used to assess bone height and density at baseline and at 6 months. Core biopsies were obtained for histologic analysis. Results: Both groups showed significant increases in bone height and density (p < 0.001). Mean bone density gain was 618.65 ± 232.20 HU (ADDM) vs. 540.87 ± 238.02 HU (xenograft, p = 0.49). Mean bone height gain was 9.34 ± 1.38 mm (ADDM) vs. 9.12 ± 1.13 mm (xenograft, p = 0.724). Histology showed viable new bone, with ADDM exhibiting higher collagen fiber density and vascularization. Conclusion: ADDM provided clinical, radiographic, and histologic outcomes comparable to those of xenografts, confirming its favorable osteoconductive properties.